| 03/29/2025 | Johnson City Doughboys | White Sox | 9:00AM - 10:45AM | James K. Ellis Athletic Complex / Field 4 | |
| 03/29/2025 | Athlete's Edge Pirates | Mariners | 11:00AM - 12:45PM | James K. Ellis Athletic Complex / Field 4 | |
| 03/29/2025 | Johnson City Doughboys | Preferred Choice Homes Orioles | 1:00PM - 2:45PM | James K. Ellis Athletic Complex / Field 4 | |
| 04/02/2025 | Mariners | Preferred Choice Homes Orioles | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | Rescheduled |
| 04/02/2025 | White Sox | Athlete's Edge Pirates | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | Rescheduled |
| 04/03/2025 | Preferred Choice Homes Orioles | Athlete's Edge Pirates | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | Rescheduled |
| 04/03/2025 | Johnson City Doughboys | Mariners | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | |
| 04/09/2025 | Mariners | White Sox | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | Rescheduled |
| 04/09/2025 | Athlete's Edge Pirates | Johnson City Doughboys | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | Rescheduled |
| 04/14/2025 | Preferred Choice Homes Orioles | Johnson City Doughboys | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | |
| 04/14/2025 | Mariners | White Sox | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | Rescheduled |
| 04/17/2025 | Johnson City Doughboys | Preferred Choice Homes Orioles | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | |
| 04/17/2025 | Athlete's Edge Pirates | White Sox | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | |
| 04/21/2025 | White Sox | Johnson City Doughboys | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | Rescheduled |
| 04/23/2025 | Preferred Choice Homes Orioles | Athlete's Edge Pirates | 7:15PM - 7:45PM | Keystone Park / Henry Joy Field 2 | Rescheduled |
| 04/24/2025 | Johnson City Doughboys | Athlete's Edge Pirates | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | |
| 04/24/2025 | Preferred Choice Homes Orioles | Mariners | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | |
| 04/28/2025 | Mariners | Johnson City Doughboys | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | |
| 04/28/2025 | White Sox | Preferred Choice Homes Orioles | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | |
| 04/29/2025 | White Sox | Athlete's Edge Pirates | 7:15PM - 9:00PM | Keystone Park / Henry Joy Field 2 | Rescheduled |
| 05/01/2025 | White Sox | Mariners | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | |
| 05/01/2025 | Athlete's Edge Pirates | Preferred Choice Homes Orioles | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | |
| 05/05/2025 | Mariners | Preferred Choice Homes Orioles | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | |
| 05/05/2025 | Athlete's Edge Pirates | Johnson City Doughboys | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | |
| 05/06/2025 | Johnson City Doughboys | White Sox | 7:15PM - 9:00PM | Keystone Park / Henry Joy Field 2 | |
| 05/08/2025 | Preferred Choice Homes Orioles | White Sox | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | Rescheduled |
| 05/08/2025 | Athlete's Edge Pirates | Mariners | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | Rescheduled |
| 05/12/2025 | Preferred Choice Homes Orioles | White Sox | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | |
| 05/12/2025 | Mariners | Johnson City Doughboys | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | |
| 05/13/2025 | Athlete's Edge Pirates | Mariners | 7:15PM - 9:00PM | Keystone Park / Henry Joy Field 2 | |
| 05/16/2025 | TBD | TBD | 7:15PM - 9:00PM | Keystone Park / Henry Joy Field 2 | |
| 05/19/2025 | TBD | TBD | 7:30PM - 9:15PM | Keystone Park / Henry Joy Field 2 | |
| 05/19/2025 | TBD | TBD | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | |
| 05/22/2025 | TBD | TBD | 7:30PM - 9:15PM | Keystone Park / Bud Rutherford Field 1 | |